Anti-Iba1 antibody [EPR16588] - Microglia marker - Rat IgG2a (Chimeric),Abcam,AB300156
Find all reagents to label astrocytes in our " Microglia markers guide ". This rat monoclonal chimeric antibody has been engineered from RabMab parent antibody ( ab178846 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using across absorbed Fc-reactive secondary antibodies are recommended. ab300156 does not react in: WB with human, mouse, and rat samples; ICC-IF with human tissues. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Rat
Reactivity
Human, Mouse, Rat
Application
IHC-P, Flow Cyt (Intra)
Platform ID
BAB408759317

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-Iba1 antibody [EPR16588] - Microglia marker - Rat IgG2a (Chimeric)
Cat. No.AB300156
HostRat
IsotypeIgG2a
ReactivityHuman, Mouse, Rat
ApplicationIHC-P, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberEPR16588
Concentration1.077 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityIon exchange chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. See full target information AIF1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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