Anti-Ikaros antibody [EPR13790] - BSA and Azide free,Abcam,AB206645
What is this antibody validated in? Anti-Ikaros antibody [EPR13790] - BSA and Azide free (ab206645) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of Ikaros? Anti-Ikaros [EPR13790] - BSA and Azide free (ab206645) specifically detects a band for Ikaros (UniProt: Q13422) at a molecular weight of 58kDa. Specificity confirmed The specificity of Anti-Ikaros antibody [EPR13790] - BSA and Azide free (ab206645) has been confirmed by Western blot testing in IKZF1 Knockout Jurkat cell line, ab274920 . Other related products We have a range of other formats of antibody clone [EPR13790] also available for your convenience: ab191394 , Carrier free - ab206645, PE - ab306120 , APC - ab306121 , HRP - ab306122 , Alkaline Phosphatase - ab308943 , Alexa Fluor® 488 - ab309879 , Alexa Fluor® 647 - ab310246 , Alexa Fluor® 594 - ab310699 , Alexa Fluor® 555 - ab312229 , Alexa Fluor® 568 - ab312718 , Alexa Fluor® 750 - ab321321 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.
Host
Rabbit
Reactivity
Mouse, Human
Application
Flow Cyt (Intra), IHC-P, WB
Platform ID
BAB224414052
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcription regulator of hematopoietic cell differentiation (PubMed : 17934067). Binds gamma-satellite DNA (PubMed : 17135265, PubMed : 19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed : 17135265, PubMed : 17934067). See full target information IKZF1
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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