Anti-Integrin alpha 2 antibody [EPR5788],Abcam,AB133557

What is this antibody validated in? Anti-Integrin alpha 2 antibody [EPR5788] (ab133557) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of Integrin alpha 2? Anti-Integrin alpha 2 [EPR5788] (ab133557) specifically detects a band for Integrin alpha 2 (UniProt: P17301) at a molecular weight of 129kDa. Trusted by the scientific community Anti-Integrin alpha 2 [EPR5788] (ab133557) was first used in a scientific publication in 2012 and has been cited over 50 times in peer-reviewed journals. Reviewed by scientists Anti-Integrin alpha 2 [EPR5788] (ab133557) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Integrin alpha 2 antibody [EPR5788] (ab133557) has been confirmed by Immunocytochemistry testing in ITGA2 Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EPR5788] also available for your convenience: ab133557, Carrier free - ab221214 , Carrier free - ab271894 , PE - ab317897 , APC - ab317935 , Alexa Fluor® 488 - ab317975 , Alexa Fluor® 594 - ab318016 , Alexa Fluor® 555 - ab318058 , Alexa Fluor® 647 - ab318100 , Alexa Fluor® 750 - ab321053 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Species reactivity Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, IHC-P

Platform ID

BAB794241783

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Integrin alpha 2 antibody [EPR5788]
Cat. No.AB133557
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberEPR5788
Concentration0.144 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.. (Microbial infection) Integrin ITGA2 : ITGB1 acts as a receptor for Human rotavirus A.. (Microbial infection) Integrin ITGA2 : ITGB1 acts as a receptor for Human echoviruses 1 and 8. See full target information ITGA2

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