Anti-Integrin alpha 6 antibody [EPR18124],Abcam,AB181551
What is this antibody validated in? Anti-Integrin alpha 6 antibody [EPR18124] (ab181551) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr) in Human, Mouse, Rat samples. What is the molecular weight of Integrin alpha 6? Anti-Integrin alpha 6 [EPR18124] (ab181551) specifically detects a band for Integrin alpha 6 (UniProt: P23229) at a molecular weight of 127kDa. Trusted by the scientific community Anti-Integrin alpha 6 [EPR18124] (ab181551) was first used in a scientific publication in 2015 and has been cited over 30 times in peer-reviewed journals. Reviewed by scientists Anti-Integrin alpha 6 [EPR18124] (ab181551) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Integrin alpha 6 antibody [EPR18124] (ab181551) has been confirmed by Western blot testing in ITGA6 Knockout SW480 cell line, ab265838 . Other related products We have a range of other formats of antibody clone [EPR18124] also available for your convenience: ab181551, Carrier free - ab240252 , Alexa Fluor® 488 - ab311018 , Alexa Fluor® 647 - ab311146 , Alexa Fluor® 594 - ab311787 , Alexa Fluor® 568 - ab313068 , Alexa Fluor® 555 - ab313265 , Alexa Fluor® 750 - ab321254 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-P, IHC-Fr, WB
Platform ID
BAB482035392
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Integrin alpha-6/beta-1 (ITGA6 : ITGB1) is a receptor for laminin on platelets (By similarity). Integrin alpha-6/beta-1 (ITGA6 : ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-6/beta-4 (ITGA6 : ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760). ITGA6 : ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed : 28873464). See full target information ITGA6
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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