Anti-Interferon alpha 1 antibody [F18],Abcam,AB7373

With the availability of monoclonal antibodies directed against alpha Interferon, it is possible to interpret results obtained from crude materials containing both alpha and beta Interferon. The difficulties in studying in vitro and in vivo effects of "type 1" Interferons arise from the fact that both alpha and beta Interferons are produced in response to the same stimuli and also seem to act via the same receptor. These Interferon activities can only be distinguished from one another by use of specific neutralizing antibodies.

Host

Rat

Reactivity

Mouse

Application

AP, FuncS (Neut/Block), Flow Cyt

Platform ID

BAB232810020

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Interferon alpha 1 antibody [F18]
Cat. No.AB7373
HostRat
IsotypeIgG1
ReactivityMouse
ApplicationAP, FuncS (Neut/Block), Flow Cyt
ClonalityMonoclonal
Clone NumberF18
Concentration0.1 mg/mL Batch dependent concentration
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes : a protein kinase and an oligoadenylate synthetase. See full target information Ifna1

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