Anti-KAT13C / NCOA2 antibody,Abcam,AB84140

Target data Transcriptional coactivator for steroid receptors and nuclear receptors (PubMed : 23508108, PubMed : 8670870, PubMed : 9430642). Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) (PubMed : 23508108, PubMed : 8670870, PubMed : 9430642). Required with NCOA1 to control energy balance between white and brown adipose tissues (PubMed : 23508108, PubMed : 8670870, PubMed : 9430642). Critical regulator of glucose metabolism regulation, acts as a RORA coactivator to specifically modulate G6PC1 expression (PubMed : 23508108, PubMed : 8670870, PubMed : 9430642). Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3 (PubMed : 23508108). Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK-BMAL1 heterodimer (By similarity). See full target information NCOA2