Anti-KCNQ4 antibody [N43/6],Abcam,AB84820

Target data Pore-forming subunit of the voltage-gated potassium (Kv) channel involved in the regulation of sensory cells excitability in the cochlea (PubMed : 10025409, PubMed : 34767770). KCNQ4/Kv7.4 channel is composed of 4 pore-forming subunits assembled as tetramers (PubMed : 34767770). Promotes the outflow of potassium ions in the repolarization phase of action potential which plays a role in regulating membrane potential of excitable cells (PubMed : 10025409, PubMed : 11245603, PubMed : 34767770). The channel conducts a slowly activating and deactivating current (PubMed : 10025409, PubMed : 11245603). Current often shows some inward rectification at positive potentials (PubMed : 10025409). Channel may be selectively permeable in vitro to other cations besides potassium, in decreasing order of affinity K(+) = Rb(+) > Cs(+) > Na(+) (PubMed : 10025409). Important for normal physiological function of inner ear such as sensory perception of sound (PubMed : 10025409, PubMed : 10369879). See full target information KCNQ4