Anti-KDM6B / JMJD3 antibody,Abcam,AB38113
What is this antibody validated in? Anti-KDM6B / JMJD3 antibody (ab38113) is a rabbit polyclonal antibody and is validated for use in Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. Trusted by the scientific community Anti-KDM6B / JMJD3 (ab38113) was first used in a scientific publication in 2007 and has been cited over 50 times in peer-reviewed journals. Reviewed by scientists Anti-KDM6B / JMJD3 (ab38113) has over 10 independent reviews from customers.
Host
Rabbit
Reactivity
Human
Application
ICC/IF, IHC-P
Platform ID
BAB926700701
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed : 17713478, PubMed : 17825402, PubMed : 17851529, PubMed : 18003914). Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed : 17713478, PubMed : 17825402, PubMed : 17851529, PubMed : 18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed : 17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed : 17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (By similarity). See full target information KDM6B
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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