Anti-KHSRP antibody,Abcam,AB264265

Host

Rabbit

Reactivity

Human

Application

IP, IHC-P

Platform ID

BAB926900605

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-KHSRP antibody
Cat. No.AB264265
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, IHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human KHSRP aa 650 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: Tris citrate/phosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs. See full target information KHSRP

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