Anti-KSR1 antibody [EPR2421Y],Abcam,AB68483
What is this antibody validated in? Anti-KSR1 antibody [EPR2421Y] (ab68483) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. What is the molecular weight of KSR1? Anti-KSR1 [EPR2421Y] (ab68483) specifically detects a band for KSR1 (UniProt: Q8IVT5) at a molecular weight of 102kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-KSR1 antibody [EPR2421Y] (ab68483) has been confirmed by Western blot testing in KSR1 Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EPR2421Y] also available for your convenience: ab68483, Carrier free - ab227109 , Alexa Fluor® 488 - ab320300 , Alexa Fluor® 647 - ab320301 , Alexa Fluor® 555 - ab320302 , Alexa Fluor® 594 - ab320303 , PE - ab320304 , APC - ab320305 , Alexa Fluor® 750 - ab321693 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-P, WB
Platform ID
BAB429449381
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases (By similarity). Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed : 29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP (By similarity). Its kinase activity is unsure (By similarity). Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown (By similarity). See full target information KSR1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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