Anti-Kallikrein 7/KLK7 antibody,Abcam,AB244367

Host

Rabbit

Reactivity

Human

Application

WB, ICC/IF

Platform ID

BAB112345342

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Kallikrein 7/KLK7 antibody
Cat. No.AB244367
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human KLK7 aa 100-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. See full target information KLK7

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