Anti-Kir6.1/KCNJ8 antibody [S366-60],Abcam,AB241996

Host

Mouse

Reactivity

Rat, Human

Application

WB, ICC/IF

Platform ID

BAB990581288

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Kir6.1/KCNJ8 antibody [S366-60]
Cat. No.AB241996
HostMouse
IsotypeIgG2a
ReactivityRat, Human
ApplicationWB, ICC/IF
ClonalityMonoclonal
Clone NumberS366-60
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Rat ATP-sensitive inward rectifier potassium channel 8 aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity). See full target information KCNJ8

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