Anti-LACTB antibody,Abcam,AB244455

Target data Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed : 28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism (PubMed : 28329758). It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein (PubMed : 28329758). Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells : probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism (PubMed : 28329758). See full target information LACTB