Anti-LC3C antibody,Abcam,AB244212

Host

Rabbit

Reactivity

Human

Application

WB, ICC/IF

Platform ID

BAB557510411

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-LC3C antibody
Cat. No.AB244212
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human MAP1LC3C aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLyophilized
ShippingBlue Ice
FormulationpH: 7 - 7.4
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2 (PubMed : 23022382). Recruits all ATG8 family members to infecting bacteria such as S.typhimurium (PubMed : 23022382). May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins (PubMed : 28404643). See full target information MAP1LC3C

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