Anti-LDL Receptor antibody [032] - BSA and Azide free,Abcam,AB277134

Host

Rabbit

Reactivity

Mouse

Application

ICC, Flow Cyt

Platform ID

BAB057860243

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-LDL Receptor antibody [032] - BSA and Azide free
Cat. No.AB277134
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationICC, Flow Cyt
ClonalityMonoclonal
Clone Number032
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Mouse Low-density lipoprotein receptor aa 1-800. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Forms a ternary complex with PGRMC1 and TMEM97 receptors which increases LDLR-mediated LDL internalization. See full target information Low-density lipoprotein receptor

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