Anti-LETM1 antibody,Abcam,AB241155

Host

Rabbit

Reactivity

Human

Application

IP, WB

Platform ID

BAB495828768

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-LETM1 antibody
Cat. No.AB241155
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human Mitochondrial proton/calcium exchanger protein aa 600-700. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: Tris citrate/phosphate
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport (PubMed : 18628306, PubMed : 19797662, PubMed : 24344246, PubMed : 24898248, PubMed : 29123128, PubMed : 32139798, PubMed : 36055214, PubMed : 36321428). Mediates proton-dependent calcium efflux from mitochondrion (PubMed : 19797662, PubMed : 24344246, PubMed : 29123128). Functions also as an electroneutral mitochondrial proton/potassium exchanger (PubMed : 24898248, PubMed : 36055214, PubMed : 36321428). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed : 18628306, PubMed : 36055214). Required for the maintenance of the tubular shape and cristae organization (PubMed : 18628306, PubMed : 32139798). See full target information Mitochondrial proton/calcium exchanger protein

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