Anti-LRRK1 antibody,Abcam,AB228666
Host
Rabbit
Reactivity
Human
Application
WB
Platform ID
BAB686970769
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-LRRK1 antibody
Cat. No.AB228666
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration1.75 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human LRRK1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Serine/threonine-protein kinase which phosphorylates RAB proteins involved in intracellular trafficking (PubMed : 36040231). Phosphorylates RAB7A; this activity is dependent on protein kinase C (PKC) activation (PubMed : 36040231, PubMed : 37558661, PubMed : 37857821). Plays a role in the negative regulation of bone mass, acting through the maturation of osteoclasts (By similarity). See full target information LRRK1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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