Anti-LRSAM1 antibody,Abcam,AB73113

Target data E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed : 15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed : 23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed : 23245322, PubMed : 25484098). See full target information LRSAM1