Anti-Lamin B1 antibody [EPR22165-121] - Nuclear Envelope Marker,Abcam,AB229025
What is this antibody validated in? Anti-Lamin B1 antibody [EPR22165-121] (ab229025) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), Multiplex IHC (mIHC) in Human, Mouse, Rat samples. What is the molecular weight of Lamin B1? Anti-Lamin B1 [EPR22165-121] (ab229025) specifically detects a band for Lamin B1 (UniProt: P20700) at a molecular weight of 66kDa. Trusted by the scientific community Anti-Lamin B1 [EPR22165-121] (ab229025) was first used in a scientific publication in 2018 and has been cited over 10 times in peer-reviewed journals. Reviewed by scientists Anti-Lamin B1 [EPR22165-121] (ab229025) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Lamin B1 antibody [EPR22165-121] (ab229025) has been confirmed by Western blot testing in LMNB1 Knockout HeLa cell line, ab255404 . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB, ICC/IF, Flow Cyt (Intra), mIHC, IHC-P, IP
Platform ID
BAB868517378
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed : 28716252, PubMed : 32910914). Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics (PubMed : 28716252, PubMed : 32910914). The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively (PubMed : 28716252, PubMed : 32910914). See full target information LMNB1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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