Anti-Lamin B1 antibody - Nuclear Envelope Marker,Abcam,AB16048
Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P and WB. Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) was first used in a scientific publication in 1997 and has been cited over 1182 times in peer reviewed journals. It's performance in Western blot and immunofluorescence in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) has high sensitivity and specificity. The specificity of Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) has been confirmed by ICC/IF testing in Lamin B1 knockout HAP1 cells. Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) has 108 independent reviews from customers. Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) specifically detects Lamin B1 (UniProt ID: P14733; Molecular weight: 67kDa) and is sold in 100 ug selling sizes. Top cited with >1500 citations. Lamin B1 is essential for studying nuclear envelope structure and function, as well as investigating diseases like laminopathies and certain cancers
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
ICC/IF, WB, IHC-P
Platform ID
BAB743554860
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed : 28716252, PubMed : 32910914). Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics (PubMed : 28716252, PubMed : 32910914). The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively (PubMed : 28716252, PubMed : 32910914). See full target information LMNB1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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