Anti-Lamin B2 antibody,Abcam,AB97513

Host

Rabbit

Reactivity

Human, Mouse

Application

WB, IP, IHC-P

Platform ID

BAB306086095

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Lamin B2 antibody
Cat. No.AB97513
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationWB, IP, IHC-P
ClonalityPolyclonal
Concentration1.73 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human LMNB2 aa 200-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed : 33033404). Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics (PubMed : 33033404). The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively (PubMed : 33033404). See full target information LMNB2

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