Anti-Laminin alpha 5/LAMA5 antibody [4C7],Abcam,AB17107

This antibody reacts with the terminal globular domain of the A chain. The staining with this antibody is sensitive to fixation of paraffin tissues and use of proteolytic enzymatic treatment.

Host

Mouse

Reactivity

Human

Application

IHC-P

Platform ID

BAB993779752

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Laminin alpha 5/LAMA5 antibody [4C7]
Cat. No.AB17107
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone Number4C7
Concentration0.95 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human LAMA5.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 - 7.5 Preservative: 0.05% Sodium azide Constituents: Tissue culture supernatant, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2 (PubMed : 33242826). See full target information LAMA5

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