Anti-Lass5 antibody,Abcam,AB63927

This product is manufactured by BioVision, an Abcam company and was previously called 3830 LASS5 Antibody. 3830-100 is the same size as the 100 µg size of ab63927.

Host

Rabbit

Reactivity

Human

Application

WB

Platform ID

BAB932098109

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Lass5 antibody
Cat. No.AB63927
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CERS5. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA; C16 : 0-CoA) (PubMed : 16951403, PubMed : 18541923, PubMed : 22144673, PubMed : 22661289, PubMed : 23530041, PubMed : 26887952, PubMed : 29632068, PubMed : 31916624). Can use other acyl donors, but with less efficiency (By similarity). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively (PubMed : 31916624). Plays a role in de novo ceramide synthesis and surfactant homeostasis in pulmonary epithelia (By similarity). See full target information CERS5

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.