Anti-Liprin alpha 2 antibody,Abcam,AB155411

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB, ICC/IF

Platform ID

BAB872415506

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Liprin alpha 2 antibody
Cat. No.AB155411
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration0.98 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PPFIA2 aa 100-450. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines (PubMed : 30021165). See full target information PPFIA2

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