Anti-MADH7/SMAD7 antibody,Abcam,AB216428
What is this antibody validated in? Anti-MADH7/SMAD7 antibody (ab216428) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of MADH7/SMAD7? Anti-MADH7/SMAD7 (ab216428) specifically detects a band for MADH7/SMAD7 (UniProt: O15105) at a molecular weight of 46kDa. Trusted by the scientific community Anti-MADH7/SMAD7 (ab216428) was first used in a scientific publication in 2016 and has been cited over 50 times in peer-reviewed journals.
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB, Flow Cyt, ICC/IF, IHC-P
Platform ID
BAB939494557
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access (PubMed : 21791611). Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. See full target information SMAD7
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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