Anti-MAFA antibody,Abcam,AB85008

Concentration is optimized for IHC and not determined

Host

Rabbit

Reactivity

Mouse

Application

IHC-P

Platform ID

BAB064557027

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MAFA antibody
Cat. No.AB85008
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Mouse Mafa aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcriptional factor that activates insulin gene expression (PubMed : 12368292, PubMed : 15665000). Acts synergistically with NEUROD1/BETA2 and PDX1 (PubMed : 15665000). Binds the insulin enhancer C1/RIPE3b element (PubMed : 12917329, PubMed : 14680841, PubMed : 14973194, PubMed : 15665000). Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence (By similarity). See full target information Mafa

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