Anti-MCP1 antibody [2.2-4H5-1A11],Abcam,AB9858

This product is no longer batch tested in IHC, for an IHC validated antibody please see ab73680

Host

Mouse

Reactivity

Human

Application

ELISA, IHC-P, WB, sELISA

Platform ID

BAB005674040

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-MCP1 antibody [2.2-4H5-1A11]
Cat. No.AB9858
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationELISA, IHC-P, WB, sELISA
ClonalityMonoclonal
Clone Number2.2-4H5-1A11
ImmunogenRecombinant Full Length Protein corresponding to Human CCL2.
PurityAffinity purification Protein A
Appearance/FormLyophilized
ShippingBlue Ice
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a ligand for C-C chemokine receptor CCR2 (PubMed : 10529171, PubMed : 10587439, PubMed : 9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed : 10587439, PubMed : 9837883). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed : 8195247, PubMed : 8627182, PubMed : 9792674). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed : 8107690). See full target information CCL2

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