Anti-MCP1 antibody,Abcam,AB25124

What is this antibody validated in? Anti-MCP1 antibody (ab25124) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Neutralising in Mouse, Rat samples. Trusted by the scientific community Anti-MCP1 (ab25124) was first used in a scientific publication in 2005 and has been cited over 160 times in peer-reviewed journals. Reviewed by scientists Anti-MCP1 (ab25124) has over 5 independent reviews from customers.

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB, IHC-P, FuncS (Neut/Block), Flow Cyt

Platform ID

BAB630686534

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MCP1 antibody
Cat. No.AB25124
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationWB, IHC-P, FuncS (Neut/Block), Flow Cyt
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Rat Ccl2 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity). See full target information Ccl2

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