Anti-MCT 10 antibody,Abcam,AB121519

Host

Rabbit

Reactivity

Human

Application

IHC-P, ICC/IF

Platform ID

BAB818530119

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-MCT 10 antibody
Cat. No.AB121519
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, ICC/IF
ClonalityPolyclonal
Concentration0.08 - 0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human SLC16A10 aa 450 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Sodium- and proton-independent thyroid hormones and aromatic acids transporter (PubMed : 11827462, PubMed : 18337592, PubMed : 28754537). Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels (PubMed : 18337592). Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa) (PubMed : 11827462, PubMed : 28754537). Plays an important role in homeostasis of aromatic amino acids (By similarity). See full target information SLC16A10

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