Anti-MD2 antibody,Abcam,AB24182

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB381161306

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MD2 antibody
Cat. No.AB24182
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, ICC/IF, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human LY96. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binds bacterial lipopolysaccharide (LPS) (PubMed : 17569869, PubMed : 17803912). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed : 11160242, PubMed : 11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed : 10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed : 10359581). See full target information LY96

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