Anti-MDH1 antibody,Abcam,AB78971
Host
Sheep
Reactivity
Human
Application
IHC-P
Platform ID
BAB131336222
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-MDH1 antibody
Cat. No.AB78971
HostSheep
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration10 mg/mL Batch dependent concentration
ImmunogenFull Length Protein corresponding to Human MDH1. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.87% Sodium chloride, 0.42% Tripotassium orthophosphate
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed : 2449162, PubMed : 3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed : 31538237). Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS) (PubMed : 34012073). See full target information MDH1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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