Anti-MDH1 antibody,Abcam,AB175455
Host
Goat
Reactivity
Mouse, Rat, Human, Pig
Application
WB
Platform ID
BAB818829975
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-MDH1 antibody
Cat. No.AB175455
HostGoat
IsotypeIgG
ReactivityMouse, Rat, Human, Pig
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human MDH1 aa 100-150. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed : 2449162, PubMed : 3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed : 31538237). Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS) (PubMed : 34012073). See full target information MDH1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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