Anti-MDMX/MDM4 antibody,Abcam,AB222905
Host
Rabbit
Reactivity
Mouse, Human
Application
WB
Platform ID
BAB194017385
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-MDMX/MDM4 antibody
Cat. No.AB222905
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human MDM4 aa 200-350. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Along with MDM2, contributes to TP53 regulation (PubMed : 32300648). Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. See full target information MDM4
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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