Anti-MDMX/MDM4 antibody [BL-3-2F2],Abcam,AB243859
REACH authorisation Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances. It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses. This product is sold under License from Bethyl Laboratories, Inc.
Host
Rabbit
Reactivity
Human
Application
Flow Cyt, IP, WB
Platform ID
BAB819029879
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-MDMX/MDM4 antibody [BL-3-2F2]
Cat. No.AB243859
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationFlow Cyt, IP, WB
ClonalityMonoclonal
Clone NumberBL-3-2F2
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human MDM4 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.8 - 8.6 Preservative: 0.09% Sodium azide Constituents: 98% Borate buffered saline, 0.1% BSA
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Along with MDM2, contributes to TP53 regulation (PubMed : 32300648). Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. See full target information MDM4
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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