Anti-MEF2C antibody [EPR19089-202] - ChIP Grade,Abcam,AB211493
What is this antibody validated in? Anti-MEF2C antibody [EPR19089-202] - ChIP Grade (ab211493) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP in Human, Mouse, Rat samples. What is the molecular weight of MEF2C? Anti-MEF2C [EPR19089-202] - ChIP Grade (ab211493) specifically detects a band for MEF2C (UniProt: Q06413) at a molecular weight of 51kDa. Trusted by the scientific community Anti-MEF2C [EPR19089-202] - ChIP Grade (ab211493) was first used in a scientific publication in 2018 and has been cited over 10 times in peer-reviewed journals. Reviewed by scientists Anti-MEF2C [EPR19089-202] - ChIP Grade (ab211493) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-MEF2C antibody [EPR19089-202] - ChIP Grade (ab211493) has been confirmed by Western blot testing in MEF2C Knockout THP-1 cell line, ab313739 . Other related products We have a range of other formats of antibody clone [EPR19089-202] also available for your convenience: ab211493, Carrier free - ab231859 , ab309199 , Alexa Fluor® 488 - ab319010 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
Flow Cyt (Intra), ChIP, WB, ICC/IF, IHC-P
Platform ID
BAB694567121
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoforms that lack the repressor domain are more active than isoform 1. See full target information MEF2C
Category Paths
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