Anti-MGMT antibody [MT3.1],Abcam,AB39253

What is this antibody validated in? Anti-MGMT antibody [MT3.1] (ab39253) is a mouse recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of MGMT? Anti-MGMT [MT3.1] (ab39253) specifically detects a band for MGMT (UniProt: P16455) at a molecular weight of 22kDa. Trusted by the scientific community Anti-MGMT [MT3.1] (ab39253) was first used in a scientific publication in 2006 and has been cited over 10 times in peer-reviewed journals. Reviewed by scientists Anti-MGMT [MT3.1] (ab39253) has over 5 independent reviews from customers. Specificity confirmed The specificity of Anti-MGMT antibody [MT3.1] (ab39253) has been confirmed by Immunocytochemistry testing in MGMT Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [MT3.1] also available for your convenience: ab39253, Carrier free - ab255966 What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Mouse

Reactivity

Human

Application

WB, IHC-P

Platform ID

BAB322178367

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MGMT antibody [MT3.1]
Cat. No.AB39253
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberMT3.1
Concentration1.05 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 - 7.5 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction : the enzyme is irreversibly inactivated. See full target information MGMT

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