Anti-MIF antibody,Abcam,AB7207

Host

Rabbit

Reactivity

Mouse, Rat

Application

IHC-P, WB, ICC/IF, ELISA, IP, IHC-Fr

Platform ID

BAB822828055

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MIF antibody
Cat. No.AB7207
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationIHC-P, WB, ICC/IF, ELISA, IP, IHC-Fr
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Rat Mif.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.5 Preservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens (By similarity). The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense (By similarity). Counteracts the anti-inflammatory activity of glucocorticoids (By similarity). Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known (PubMed : 10933783, PubMed : 16780921, PubMed : 19188446). It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (PubMed : 10933783, PubMed : 16780921, PubMed : 19188446). See full target information Mif

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