Anti-MMP9 antibody [EP1254],Abcam,AB76003

Product Specifications Anti-MMP9 antibody [EP1254] (ab76003) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, WB in human, rat, samples. Anti-MMP9 antibody [EP1254] (ab76003) specifically detects MMP9 (UniProt ID: P14780; Molecular weight: 1kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-MMP9 antibody [EP1254] (ab76003) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-MMP9 antibody [EP1254] (ab76003) has been cited over 551 times in peer reviewed journals and is trusted by the scientific community. Anti-MMP9 antibody [EP1254] (ab76003) has 12 independent reviews from customers. Related Products Antibody clone EP1254 is also available pre-conjugated to a variety of labels for your convenience - PE, APC, HRP, Alkaline Phosphatase, Alexa Fluor® 488, Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 555, Alexa Fluor® 568, Alexa Fluor® 750 ( ab305635 , ab305636 , ab305637 , ab308802 , ab309755 , ab310122 , ab310533 , ab312063 , ab312540 , ab321706 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Rat, Human

Application

WB, Flow Cyt (Intra), ICC/IF, IHC-P

Platform ID

BAB262595716

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MMP9 antibody [EP1254]
Cat. No.AB76003
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationWB, Flow Cyt (Intra), ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberEP1254
Concentration2.02 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (PubMed : 12879005, PubMed : 1480034, PubMed : 2551898). Could play a role in bone osteoclastic resorption (By similarity). Cleaves KiSS1 at a Gly-|-Leu bond (PubMed : 12879005). Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed : 32883094). Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (PubMed : 1480034). Degrades fibronectin but not laminin or Pz-peptide. See full target information MMP9

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