Anti-MRPL41 antibody,Abcam,AB121821

Host

Rabbit

Reactivity

Human

Application

WB, ICC/IF, IHC-P

Platform ID

BAB639382358

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-MRPL41 antibody
Cat. No.AB121821
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF, IHC-P
ClonalityPolyclonal
Concentration0.3 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human MRPL41 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the mitochondrial ribosome large subunit (PubMed : 25278503, PubMed : 25838379, PubMed : 28892042, PubMed : 35177605). Also involved in apoptosis and cell cycle (PubMed : 16024796, PubMed : 16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed : 16024796). See full target information MRPL41

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