Anti-MSH3 antibody [RM405] - BSA and Azide free,Abcam,AB322511
ab322511 is the carrier-free version of ab275928 What is this antibody validated in? Anti-MSH3 antibody [RM405] ( ab275928 ) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of MSH3? Anti-MSH3 [RM405] ( ab275928 ) specifically detects a band for MSH3 (UniProt: P20585) at a molecular weight of 127kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-MSH3 antibody [RM405] ( ab275928 ) has been confirmed by Western blot testing in MSH3 Knockout A549 cell line, ab288875 .
Host
Rabbit
Reactivity
Human, Mouse
Application
IHC-P, WB
Platform ID
BAB264894612
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. See full target information MSH3
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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