Anti-MST4 antibody [EP1864Y],Abcam,AB52491
Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IP, Flow Cyt (Intra), IHC-P, WB, ICC/IF
Platform ID
BAB452738197
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Serine/threonine-protein kinase that acts as a mediator of cell growth (PubMed : 11641781, PubMed : 17360971). Modulates apoptosis (PubMed : 11641781, PubMed : 17360971). In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed : 27807006). Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux (PubMed : 29232556). Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (PubMed : 18782753). See full target information STK26
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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