Anti-MST4 antibody [EP1864Y] - BSA and Azide free,Abcam,AB284689

ab284689 is the carrier-free version of ab52491 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Host

Rabbit

Reactivity

Rat, Human, Mouse

Application

IP, WB, IHC-P, ICC/IF, Flow Cyt (Intra)

Platform ID

BAB765244444

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MST4 antibody [EP1864Y] - BSA and Azide free
Cat. No.AB284689
HostRabbit
IsotypeIgG
ReactivityRat, Human, Mouse
ApplicationIP, WB, IHC-P, ICC/IF, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberEP1864Y
Concentration0.997 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Serine/threonine-protein kinase that acts as a mediator of cell growth (PubMed : 11641781, PubMed : 17360971). Modulates apoptosis (PubMed : 11641781, PubMed : 17360971). In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed : 27807006). Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux (PubMed : 29232556). Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (PubMed : 18782753). See full target information STK26

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