Anti-MUC1 antibody [EP1024Y],Abcam,AB45167

What is this antibody validated in? Anti-MUC1 antibody [EP1024Y] (ab45167) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. Trusted by the scientific community Anti-MUC1 [EP1024Y] (ab45167) was first used in a scientific publication in 2006 and has been cited over 30 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-MUC1 antibody [EP1024Y] (ab45167) has been confirmed by Western blot testing in Mucin-1 Knockout HeLa cells. Other related products We have a range of other formats of antibody clone [EP1024Y] also available for your convenience: ab45167, PE - ab213337 , Carrier free - ab218998 , Carrier free - ab256588 , APC - ab317951 , Alexa Fluor® 488 - ab317992 , Alexa Fluor® 594 - ab318034 , Alexa Fluor® 555 - ab318076 , Alexa Fluor® 647 - ab318117 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

Flow Cyt, IP, ICC/IF, WB

Platform ID

BAB828925127

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MUC1 antibody [EP1024Y]
Cat. No.AB45167
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationFlow Cyt, IP, ICC/IF, WB
ClonalityMonoclonal
Clone NumberEP1024Y
Concentration0.119 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. See full target information Mucin-1

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