Anti-MUC1 antibody [EPR1023],Abcam,AB109185

Product Specifications Anti-MUC1 antibody [EPR1023] (ab109185) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in human, mouse, rat samples. Anti-MUC1 antibody [EPR1023] (ab109185) specifically detects MUC1 (UniProt ID: P15941; Molecular weight: 120kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-MUC1 antibody [EPR1023] (ab109185) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-MUC1 antibody [EPR1023] (ab109185) has been confirmed by testing in knockout samples. Anti-MUC1 antibody [EPR1023] (ab109185) has been cited over 55 times in peer reviewed journals and is trusted by the scientific community. Related Products Antibody clone EPR1023 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor® 488, PE, APC, Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 568, Alexa Fluor® 555, Alexa Fluor® 750 ( ab195936 , ab196443 , ab211592 , ab310811 , ab311079 , ab311673 , ab312948 , ab313157 , ab320930 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Shipping conditions update: ambient shipping This product will be delivered at ambient temperature instead of chilled – this is by design. Extensive stability testing confirmed that our products are suitable for shipment under ambient conditions and maintain expected quality. Why the change? It’s part of our commitment to more sustainable packaging solutions, with ambient deliveries using eco-friendly materials such as recyclable cardboard instead of polystyrene. What you need to know Ambient shipments come clearly marked on the delivery note. No ice will be included in ambient shipments, but mixed orders (ambient and cold-chain items) will still arrive with ice packs to protect temperature-sensitive products. Warranty coverage remains fully valid, aligned with our validated shipping method. Please store the product as per the datasheet instructions upon receipt. Find out more - https://www.abcam.com/en-us/support/shipping-storage-support/ambient-shipping

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

WB, Flow Cyt (Intra), IP, ICC/IF, IHC-P

Platform ID

BAB766443868

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MUC1 antibody [EPR1023]
Cat. No.AB109185
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB, Flow Cyt (Intra), IP, ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberEPR1023
Concentration0.163 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingConditional Ambient
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. See full target information MUC1

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