Anti-MX1 antibody,Abcam,AB95926

What is this antibody validated in? Anti-MX1 antibody (ab95926) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of MX1? Anti-MX1 (ab95926) specifically detects a band for MX1 (UniProt: P20591) at a molecular weight of 76kDa. Trusted by the scientific community Anti-MX1 (ab95926) was first used in a scientific publication in 2010 and has been cited over 40 times in peer-reviewed journals. Reviewed by scientists Anti-MX1 (ab95926) has over 10 independent reviews from customers.

Host

Rabbit

Reactivity

Human

Application

WB, IHC-P

Platform ID

BAB455137045

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-MX1 antibody
Cat. No.AB95926
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, IHC-P
ClonalityPolyclonal
Concentration0.06 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human MX1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs. See full target information MX1

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