Anti-Mannan Binding Lectin/MBL antibody [14D12],Abcam,AB106046

It is recommended that solutions with a calcium concentration of 1 mM are used as ab106046 is a calcium-dependent antibody.

Host

Rat

Reactivity

Mouse

Application

IHC-Fr

Platform ID

BAB690369137

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Mannan Binding Lectin/MBL antibody [14D12]
Cat. No.AB106046
HostRat
IsotypeIgG2a
ReactivityMouse
ApplicationIHC-Fr
ClonalityMonoclonal
Clone Number14D12
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Mouse Mbl2.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). See full target information Mbl2

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