Anti-Mark3 antibody,Abcam,AB264285

Target data Serine/threonine-protein kinase (PubMed : 16822840, PubMed : 16980613, PubMed : 23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed : 23666762). Phosphorylates CDC25C on 'Ser-216' (PubMed : 12941695). Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed : 16980613). Regulates localization and activity of MITF by mediating its phosphorylation, promoting subsequent interaction between MITF and 14-3-3 and retention in the cytosol (PubMed : 16822840). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed : 28087714). Phosphorylates PKP2 and KSR1 (PubMed : 12941695). See full target information MARK3