Anti-Mast Cell Tryptase antibody [AA1],Abcam,AB2378

Product Specifications Anti-Mast Cell Tryptase antibody [AA1] (ab2378) is a mouse monoclonal antibody and is validated for use in IHC-P, WB in human samples. Anti-Mast Cell Tryptase antibody [AA1] (ab2378) specifically detects Mast Cell Tryptase (UniProt ID: P20231; Molecular weight: 28kDa) and is sold in 100 µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-Mast Cell Tryptase antibody [AA1] (ab2378) has high sensitivity and specificity. Anti-Mast Cell Tryptase antibody [AA1] (ab2378) has been cited over 146 times in peer reviewed journals and is trusted by the scientific community. Anti-Mast Cell Tryptase antibody [AA1] (ab2378) has 35 independent reviews from customers. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Human

Application

IHC-P, WB

Platform ID

BAB754249724

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Mast Cell Tryptase antibody [AA1]
Cat. No.AB2378
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone NumberAA1
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed : 18854315). See full target information TPSAB1

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