Anti-Metabotropic Glutamate Receptor 5 antibody [EPR2425Y],Abcam,AB76316

What is this antibody validated in? Anti-Metabotropic Glutamate Receptor 5 antibody [EPR2425Y] (ab76316) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Electron microscopy (EM) in Human, Mouse, Rat samples. What is the molecular weight of Metabotropic Glutamate Receptor 5? Anti-Metabotropic Glutamate Receptor 5 [EPR2425Y] (ab76316) specifically detects a band for Metabotropic Glutamate Receptor 5 (UniProt: P41594) at a molecular weight of 132kDa. Trusted by the scientific community Anti-Metabotropic Glutamate Receptor 5 [EPR2425Y] (ab76316) was first used in a scientific publication in 2009 and has been cited over 40 times in peer-reviewed journals. Reviewed by scientists Anti-Metabotropic Glutamate Receptor 5 [EPR2425Y] (ab76316) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR2425Y] also available for your convenience: ab76316, HRP - ab196482 , Carrier free - ab219374 , Carrier free - ab256589 , APC - ab310880 , PE - ab310939 , Alexa Fluor® 488 - ab310960 , Alexa Fluor® 594 - ab311666 , Alexa Fluor® 568 - ab312940 , Alexa Fluor® 555 - ab313151 , Alexa Fluor® 750 - ab321725 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-Fr, WB, EM, Flow Cyt (Intra), IHC-P

Platform ID

BAB508722576

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Metabotropic Glutamate Receptor 5 antibody [EPR2425Y]
Cat. No.AB76316
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-Fr, WB, EM, Flow Cyt (Intra), IHC-P
ClonalityMonoclonal
Clone NumberEPR2425Y
Concentration0.137 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. See full target information GRM5

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