Anti-Metabotropic Glutamate Receptor 7/MGLUR7 antibody [7G8D3],Abcam,AB233722

Host

Mouse

Reactivity

Human

Application

Flow Cyt, WB

Platform ID

BAB446241317

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Metabotropic Glutamate Receptor 7/MGLUR7 antibody [7G8D3]
Cat. No.AB233722
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt, WB
ClonalityMonoclonal
Clone Number7G8D3
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human GRM7 aa 450-600. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (PubMed : 33500274). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits (PubMed : 9473604). See full target information GRM7

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